The former Test wicketkeeper wasn't included in Australia's Test squad for the upcoming tour of India, but he still won't feature for the Blues in Hobart in the match that starts on Wednesday.
Haddin is likely to replace Matthew Wade who will be heading to India early in preparation for the first Test starting 22 February.
Ben Rohrer will captain the side, with regular skipper Stephen O'Keefe ruled out after he split the webbing in his hand.
Rohrer is looking forward to leading the team in what will be just his second Shield game of the season.
"It's unfortunate for SOK (O'Keefe), he's had a few issues with that webbing over the years and it got him again on the weekend," Rohrer said.
"But it's a good opportunity for myself as the captain and also a few of the other boys to come into the side for their first games of the year."
Tim Cruickshank, Nic Maddinson and Josh Hazlewood replace Steve Smith and Moises Henriques after the duo were included in Australia's Test squad.
"We've got some really quality players around and that's going to give them a great opportunity over the next couple of months to show how good they are and hopefully cement a spot for themselves in the first XI," Rohrer said.
"We've got some guys who've played a little bit over the last couple of years who are going to get a longer crack now, so hopefully they can do the job."
Tasmania are just a point above the Blues on the table and NSW need a win to keep in touch with the leaders.
Rohrer expects a tough challenge from Tasmania, but can't wait to come up against Ricky Ponting.
"(Tasmania are) a very good side as always and they know how to play their conditions down there," Rohrer said.
"Obviously Ricky Ponting (is) in their line-up as well so it will be fantastic to play against him and I think Ben Hilfenhaus is back for his first Shield game for a quite a while.
"They're going to be tough to beat and they're in front of us on the competition so we really need to get the six points."