India captain Virat Kohli has opted to send England's batsmen in and back his players to successfully chase after winning the toss in the first one-day international at Trent Bridge.
England had been facing a selection conundrum leading into the match, with allrounder Ben Stokes fit and poised to return to the one-day XI. But the decision of who would make way was made for them, when batsman Alex Hales was ruled out due to a side injury sustained when batting in net practice.
SCORECARD: England v India, first ODI
The England and Wales Cricket Board confirmed the news on the morning of the match, with Middlesex batsman David Malan called into the squad as cover.
The in-form Hales, who averaged 48 as England lost their Twenty20 series against India 2-1, is now set to be monitored by England on a game-by-game basis.
Meanwhile, Joe Root is back in the England XI after being left out of the third T20I against India in favour of Stokes.
England's most recent ODI at Trent Bridge saw Hales make 147 as England complied a men's record total of 6-481 in a 242-run win, also a record, against Australia on June 19.
Leading into the match, India vice-captain Rohit Sharma said he and his teammates would not be intimidated even if the hosts post a high target, as they did at the same venue against Australia.
"This team (India) likes chasing down targets," said Sharma.
"Whatever we do we don't go out and bat like we have to score 400 runs. We bat normally and see where you are at 30 overs and analyse it.
"We noticed the last series played here it was high scoring games and this is where they scored 481 runs.
"I'm expecting nothing else than a high-scoring series. It's always nice to see the score in front of you and see how you can bat."
England batsman Joe Root said he wasn't going to make any wild predictions of them topping the score they posted against the Australians.
"It's dangerous to think too far ahead," said Root, who will hope to retain his place in the ODI line-up after being dropped for the final T20 match.
"One thing we have been good at is assessing things early on and planning an innings.
"It might be the case, it might not, but ultimately it's about winning the series and coming out of what has been an impressive white-ball summer."
England XI: Jason Roy, Jonny Bairstow, Joe Root, Eoin Morgan, Jos Buttler, Ben Stokes, Moeen Ali, David Willey, Liam Plunkett, Adil Rashid, Mark Wood
India XI: Rohit Sharma, Shikhar Dhawan, KL Rahul, Virat Kohli, Suresh Raina, MS Dhoni, Hardik Pandya, Siddarth Kaul, Kuldeep Yadav, Umesh Yadav, Yuzvendra Chahal